Environmental Factor - August 2023: Silicone wristbands track hundreds of unique chemical exposures

An official website of the United States government

The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. Lapel Pins

Environmental Factor - August 2023: Silicone wristbands track hundreds of unique chemical exposures

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Small, lightweight technology records pesticides, personal care products, flame retardants, and more on a global scale.

With funding from the NIEHS Superfund Research Program (SRP) and other NIEHS programs, researchers at the Oregon State University (OSU) SRP Center developed a simple, non-invasive approach to monitor personal chemical exposures using silicone wristbands. The highly sensitive wristbands can be used to measure exposure to low levels of hundreds of chemicals, offering a unique tool to better understand the complex mixtures people may be exposed to throughout daily life.

“The wristbands have many advantages compared to traditional personal monitoring approaches,” said Kim Anderson, Ph.D., an OSU SRP team lead. “They are small and lightweight, and people can wear them all day as they go about their various activities, commuting, working, cooking, exercising, and sleeping. The wristbands can answer questions about personal exposure to a range of chemicals that we hadn’t been able to address at the individual level in the past.”

People are exposed to many different chemicals in food, water, air, and products that contact the skin. Some of these exposures may be harmful to human health, but it can be difficult to capture such complex mixtures and understand how they may interact to affect health.

Historically, personal exposure sampling devices have only been capable of detecting a small range of targeted compounds or have been large and cumbersome for study participants. More accurate personal exposure data can be obtained from biological samples, such as blood or urine, but such approaches can be invasive for study participants. To gain a better understanding of the exposome — the totality of exposures a person experiences throughout life and how those exposures may lead to disease — scientists must first have better tools to capture the diverse chemical mixtures that make up an individual’s environment.

Anderson and former SRP trainee and 2012 K.C. Donnelly award winner Steven O’Connell, Ph.D., developed an approach to extract and analyze more than 1,500 chemicals from silicone wristbands, including pesticides, volatile organic contaminants, personal care products, smoke and oil compounds, flame retardants, and more. The tool provides scientists with a simple way to characterize a person’s unique environmental exposures. Knowing this can help scientists better understand how exposure to chemicals in everyday life affects human health.

The team also co-founded MyExposome Inc., a small business dedicated to monitoring individual environmental exposures.

Anderson’s early research focused on developing environmental passive sampling tools that better mimicked the amount of pollutants in water that could be taken up by a living organism and potentially pose a risk to human health.

“An SRP colleague expressed a need for similar tools to collect personal exposure data for humans, which was the nexus for building on our environmental passive sampling technology to monitor individual human exposures using silicone wristbands,” Anderson shared.

Silicone mimics the way that skin and other cells in the body absorb chemicals. When a person wears the silicone wristband, organic chemicals from the air, water, and even their skin are absorbed into the band.

When wristbands are sent back to the lab, chemicals are extracted and analyzed using a method Anderson’s lab developed to determine what chemicals are present and how much. Over the years, the team has validated the wristbands against other traditional personal exposure methods, highlighting their benefits.

“The methods used to extract and analyze chemical compounds from the wristbands is easy to learn and uses routinely available lab equipment,” said Anderson. “Coupled with ease of use in the field, these passive samplers are well suited for all different kinds of populations around the world.”

Since their development, the silicone wristbands have been used in a variety of contexts and with diverse populations. Anderson and team have also collaborated with other SRP- and NIEHS-funded researchers to understand exposures in children and adults across the U.S. and abroad as follows.

According to Anderson, the wristbands have been instrumental in making important connections between chemical exposures and toxicity, disaster events and exposures, and chemical exposures and health outcomes in populations. The wristbands also helped the research team better engage with study participants, Anderson added.

Anderson noted that most people do not feel connected with, or trusting of, exposure models or other sources of exposure information.

“Folks want something they can hold and feel, and get their exposure data back,” she said. “The wristbands provide that physical connection that they can touch, and it helps build trust as we share results and knowledge.”

For example, the OSU SRP Center team worked with tribal partners to initiate a community-engaged study using wristbands to measure exposures to polycyclic aromatic hydrocarbons (PAHs). PAHs are contaminants produced from burning biomass, or from certain cultural and spiritual practices like burning candles or incense.

Using the wristbands and participants’ recorded diaries on daily activities, the researchers identified differences in PAH exposure among individuals and across seasons. After the team shared results with participants, community members reported feeling more aware about their potential exposure to PAHs from different sources and, in many cases, felt empowered to take steps to reduce their exposure.

The team also collaborated with researchers at the Texas A&M University SRP Center to monitor exposures after Hurricane Harvey.

“As cleanup efforts began, concerns were raised regarding the human health impacts of chemical exposures resulting from the hurricane and subsequent flooding,” Anderson said. “We used wristbands to look at personal exposures right after the hurricane, and again one year later, as a substitute baseline and were able to document that chemical exposures were generally higher following Harvey.”

According to Anderson and the team, silicone wristbands are simple, low-cost, low-maintenance, and non-invasive, making them well suited to a variety of difficult-to-reach populations and during disasters.

They further stressed how engaging communities and incorporating local knowledge into research frameworks can help promote community resilience after disasters, such as oil spills, hurricanes, and wildfires, while increasing environmental health literacy through culturally aware communication.

(This article was adapted from a Public Health Impacts story.)

(Adeline Lopez is a science writer for MDB Inc., a contractor for the NIEHS Division of Extramural Research and Training.)

Sign up for monthly newsletter updates

We will let you know when our newest issue is ready. Right in your email box!

The Environmental Factor is produced monthly by the National Institute of Environmental Health Sciences (NIEHS), Office of Communications and Public Liaison. The text is not copyrighted, and it can be reprinted without permission. If you use parts of Environmental Factor in your publication, we ask that you provide us with a copy for our records. We welcome your comments and suggestions.

Director of Communications: Christine Bruske Flowers | Editor-in-Chief: Caroline Stetler | Technical Writer-Editor: Jennifer Harker | Photo Editor: Joe Poccia

Contact Us | Freedom of Information Act | HHS Vulnerability Disclosure Policy | Staff Directory | Web Policies | Website Archive 111 T.W. Alexander Drive, Durham, NC USA 27709.

NIH...Turning Discovery Into Health

Environmental Factor - August 2023: Silicone wristbands track hundreds of unique chemical exposures

Canvas Shoe Keychain NIEHS website: Email the Web Manager at